Saving Lives Every Day

For the thousands of people diagnosed every year with life-threatening blood cancers like leukemia and lymphoma, a cure exists. Over the past 30 years Be The Match ® , operated by the National Marrow Donor Program ®  (NMDP), has managed the largest and most diverse marrow registry in the world. We work every day to save lives through transplant.

Patients depend on Be The Match and our supporters to find a match to save their life. We are here to provide one-on-one support to patients and their families every step of the way along the transplant journey. Our never-ending passion and dedication to save lives through transplant are what drive us to help more patients survive.

For patients diagnosed with leukemia, lymphoma and other life-threatening diseases, a bone marrow or cord blood transplant may be their best or only hope for a cure. Yet 70% of patients who need a transplant to do not have a fully matched donor in their family. They depend on Be The Match® and our supporters to find a match to save their life. We also provide one-on-one support to patients and their families throughout the transplant journey.


You Can Be Someone's Cure

If you are a potential match for a patient, you will be contacted at any or all steps of the patient search process:  

Step 1. During a transplant center’s preliminary search of the Be The Match Registry, when you’re ranked high on a list of potential donors who are a possible match for a patient.  

Step 2. When a patient’s doctor requests additional testing of your HLA tissue sample (that you provided when you joined the registry) to determine if you’re a good match, helping to narrow the list of potential donors.

📷Watch patients, caregivers and transplant experts explain what the donor search process is like.

Step 3. For confirmatory typing when a patient’s doctor requests a blood sample from you for additional testing to determine if you’re the best donor for the patient. 

All medical expenses related to additional testing and donation will be covered by the patient’s insurance or by Be The Match®.  


How Donors Are Selected

Matching donors and patients is much more complex than matching blood types. Doctors match donors to patients based on their human leukocyte antigen (HLA) tissue type. 

HLA are proteins, or markers, found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not. A close HLA match between donor and patient is the most important matching factor.

Matching HLA Markers

There are many HLA markers that make each person’s tissue type unique. Certain markers are key to a successful bone marrow or cord blood transplant. All new members are tested for these specific markers when they join the Be The Match Registry®. 


mabel's story

Mabel Barba is a very dear friend of ours that we met on the set of Marvel/Fox' "The Gifted".

Her love, spirit, intellect, wisdom and love of life is so infectious and she is such an extraordinary incredible light to everyone she meets and is truly beautiful – inside and out!

Mabel has worked within the movie and TV industry for over 8 years, has a Bachelor of Science Degree in Film, an Associates in Arts Degree and has worked successfully with such organizations including, Marvel, Fox, Universal, Netflix, Paramount using her skills and talents on productions including "Moonlight", "I Am Frankie", "The Unbroken", "American Crime Story: Versace", "Baywatch", "Ride Along", "Bloodline", "Graceland", "Burn Notice", "24: Legacy", "The Gifted", just to name but a few.

Mabel Barba is a very dear friend of mine, who's love, spirit, intellect, wisdom smile and life is such an extraordinary incredible light to everyone she meets and is truly beautiful – inside and out!

However, I was overwhelmed with so much grief and sadness when I heard that this beautiful lady, who exudes light, life and so much positivity, is, right now, with courageousness and boldness, fighting a rare form of Acute Myeloid Leukemia which required her to have a complete bone marrow transplant on July 8th to save her life.

We wanted to desperately focus on highlighting the need for people from ethnic minorities to register as bone marrow donors as it took Mabel nearly 6 months to find a match. (Mabel was diagnosed in December 2018 and so you can see the seriousness of discovering a suitable donor.)

Mabel is a great believer in God . Her words and positivity gives me strength to further realize that with this faith, prayers and belief, you never to be afraid of any circumstance, as the Universal Creator’s hands, guidance, provision and expertise is being manifested for good and true works!

Please, read her story, pray for her complete and whole recovery, share with family and friends, like, donate to the BeTheMatch.com or her GoFundMe page, and support Mabel and all those who are suffering from any cancer-related illness so others can be helped and have their quality of life restored and healed. Thank You.



In response to God’s call to care for the poor, Compassion gives hope to the hopeless, meeting practical needs and sharing the good news about Jesus in a culturally relevant, unconditional way to all we serve.

Sponsor A Child Today and Make A Difference!



St. Jude is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases and is also one of the world's premier treatment and care centers for children with leukemia and lymphoma.

You can help support our lifesaving mission by donating or giving your time. 

The treatment of children with leukemias, acute lymphoblastic leukemia, Hodgkin lymphoma and other acute lymphomas is complex and requires the coordinated care of many experts including pediatric oncologists, surgeons, radiation specialists, radiologists, nurses and other professionals.






As a young man, Danny Thomas had a simple goal: to entertain people and be successful enough at it to provide for his wife and family. But work wasn’t easy to come by.The Thomas Family - Danny, Marlo, Terre and Tony.

As he and his family struggled, his despair grew. He wondered if he should give up on his dreams of acting or find a steady job. He turned to St. Jude Thaddeus, the patron saint of hopeless causes. “Show me my way in life,” he vowed to the saint one night in a Detroit church, “and I will build you a shrine.”
That prayer to St. Jude marked a pivotal moment in his life. 

Soon after, he began finding work, eventually becoming one of the biggest stars of radio, film and television in his day.  And as one of the world’s biggest celebrities, Danny used his fame to fulfill his vow to St. Jude Thaddeus and to change the lives of thousands of children and families.

By 1955 Danny and a group of Memphis businessmen he’d rallied to build the hospital decided it should be more than a general children’s hospital. At the time, the survival rate for childhood cancers was 20%, and for those with acute lymphoblastic leukemia (ALL) — the most common form of childhood cancer — only 4% of children would live. They believed that St. Jude could help these families with nowhere else to turn. St. Jude would become a unique research institution where the world’s best doctors and scientists would work together to cure childhood cancer, sickle cell and other deadly diseases.And for families with children battling these diseases, Danny wanted to remove the burden of treatment costs so they were free to focus on their child.The idea of his shrine to St. Jude set, Danny and his supporters focused on raising the funds to build and maintain it.





St. Jude Children’s Research Hospital opened its doors on February 4, 1962, based on Danny's dream that "no child should die in the dawn of life." 

Since then, we’ve made incredible strides in childhood cancer research. We’ve helped improve the survival rate of childhood cancer from 20% to 80%. And ALL, the disease with a virtual death sentence in 1962, now has a survival rate of 94 percent.

Today, we’re a world leader in developing new, improved treatments for children with cancer, and we create more clinical trials for cancer than any other children's hospital. 

We freely share those breakthroughs, and every child saved at St. Jude means doctors and scientists worldwide can use that knowledge to save thousands more children.

And still today as when we opened our doors, families never receive a bill from St. Jude for treatment, travel, housing or food – because all they should worry about is helping their child live.

Danny Thomas passed away in 1991, but he left us with an enduring legacy and commitment to saving the lives of children everywhere. We won’t stop until no child dies from cancer.

Donations will help make sure that no family ever receives a bill from St. Jude for treatment, travel, housing or food — because all a family should worry about is helping their child live.

Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.





The Cancer Center supports five major interdisciplinary research programs that are organized with the specific intent of translating basic science discoveries into curative therapies for children with cancer, while minimizing long-term side effects. 

Our three disease-oriented programs focus on Developmental Biology and Solid Tumors, Hematological Malignancies, and Neurobiology and Brain Tumors; our Cancer Control and Survivorship Program strives to improve the quality of life of individuals surviving childhood cancer; and our Cancer Biology Program embeds basic cancer research within the heart of the center, facilitating direct interaction between the disease-oriented programs and the major laboratory resources in the center.

Brain tumors are the leading cause of cancer-related death in children. Despite rapid advances in our understanding of disease biology, current treatment approaches are still lacking for some patients and lead to long-term, debilitating side effects in others.

The Neurobiology and Brain Tumor Program is a collaborative, transdisciplinary research program of the St. Jude Comprehensive Cancer Center. The program aims to improve survival and morbidity for children with brain tumors by developing effective, relatively non-toxic therapies through a better understanding of disease pathogenesis.

By integrating the latest genomic and genetic technologies with studies of the developing nervous system, members of this program are efficiently translating laboratory findings into opportunities for new treatments. 

Our genome-wide studies of the major pediatric brain tumor types have identified novel mutations, defined molecular subgroups, and opened new avenues of basic, translational and clinical investigation. Exciting advances in the fields of molecular pathology, imaging and radiation oncology provide additional promise for progress in treatment of these clinically formidable diseases.




If you want to donate your time, we'd love for you to volunteer at our events, hosted across the country, as a way to give back and grow closer to our mission. Or, you can raise funds and awareness by attending events or fundraising in your community. 

Using our checks or address labels is a great way to spread our mission as well. 

Volunteer at St. Jude events across the country, and help us continue treating and researching childhood cancer and other life-threatening diseases.

Employer matching gifts, payroll deduction and workplace fundraisers are ways you can give to St. Jude.

You can raise funds by attending school, fitness or dinner events, or organizing your own effort, in your community.

DEDICATE A BRICK:  Our patient families and staff will see your words of support with every step when you engrave a brick on the pathway leading to the Kay Research and Care Center, home of the world’s first proton therapy center dedicated solely to children.

Personalized gift funds are a wonderful way to honor or remember someone special.